Plot of the Effector CAR-T cells
Plot of the Memory CAR-T cells
Plot of the Tumor cells
Plot of the all population cells
Table data of all population cells
Report
CARTmath
It simulates a three-cell mathematical model to describe tumor response to CAR-T cell immunotherapy in immunodeficient mouse models.
This mathematical model is described in the following publication:
BARROS, L.R.C.; PAIXAO, E.A.; VALLI, A.M.P.; NAOZUKA, G.T.; FASSONI, A.C.; ALMEIDA, R. C. CARTmath - A Mathematical Model of CAR-T Immunotherapy in Preclinical Studies of Hematological Cancers. Cancers, 13(12), 2021. doi: 10.3390/cancers13122941.
This simulator has been developed by the Tumor Modeling Group (TMG) from the Laboratório Nacional de Computação CientÃfica, LNCC, Brazil.
Development team:
Emanuelle Arantes Paixão
Gustavo Taiji Naozuka
Andréa Maria Pedrosa Valli
Luciana Rodrigues Carvalho Barros
Regina Célia Cerqueira de Almeida
About Us
Emanuelle Arantes Paixão
D.Sc. Student
Laboratório Nacional de Computação CientÃfica (LNCC)
Email:
earantes@lncc.br
Gustavo Taiji Naozuka
D.Sc. Student
Laboratório Nacional de Computação CientÃfica (LNCC)
Email:
naozuka@lncc.br
Andréa Maria Pedrosa Valli
Professor
Laboratório de Otimização e Modelagem Computacional
Departamento de Informática - Universidade Federal do EspÃrito Santo (UFES)
Email:
avalli@inf.ufes.br
Luciana Rodrigues Carvalho Barros
Researcher Coordinator
Fundação Faculdade de Medicina da Universidade de São Paulo (FMUSP)
Email:
lucianalpt@gmail.com
Regina Célia Cerqueira de Almeida
Senior Researcher
Laboratório Nacional de Computação CientÃfica (LNCC)
Email:
rcca@lncc.br
Warning
Embed CARTmath manual can be seen only in a browser. If you are viewing in a RStudio window, click on 'Open in Browser' (on the top left) or access the file through 'pdf' folder.
CARTmath
If you have some questions, suggestions or observations about the CARTmath, please, send us an email to the following address
tmglncc@gmail.com
Involved Institutions:
This work was financed by:
